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EvolMAP is an algorithm and software for estimating the composition of ancestral genomes and the timing of gene duplication and loss events. The input is a species-tree and genes from its modern species. The output is the inferred ancestral genes of the speciation nodes of the tree and the inferred gene duplication & loss events specific to each branch. EvolMAP features include:
Onur Sakarya, Kenneth S. Kosik and Todd H. Oakley. Reconstructing ancestral genome content based on symmetrical best alignments and Dollo parsimony. Bioinformatics 2008 24(5):606-612. |